tnfr1 signaling pathway
| PAG Title | tnfr1 signaling pathway |
| PAG ID | WAG000414 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | TNFR1 (a.k.a. p55, CD120a) is the receptor for TNF(alpha) and also will bind TNF(beta). Upon binding TNF(alpha) a TNFR1+ cell is triggered to undergo apoptosis. This critical regulatory process is accomplished by activating the proteolytic caspase cascade that results in the degradation of many critical cellular proteins. |
| Species | Homo sapiens |
| nCoCo Score | 3,785 |
| Base PAG ID | WAG000414 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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