tnfr1 signaling pathway
| PAG Title | tnfr1 signaling pathway |
| PAG ID | WAG000414 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | TNFR1 (a.k.a. p55, CD120a) is the receptor for TNF(alpha) and also will bind TNF(beta). Upon binding TNF(alpha) a TNFR1+ cell is triggered to undergo apoptosis. This critical regulatory process is accomplished by activating the proteolytic caspase cascade that results in the degradation of many critical cellular proteins. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 3,785 |
| Information Content | Rich |
| Other IDs | |
| Base PAG ID | WAG000414 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
">
Something else? Please send us an email!